Nephrotic vs Nephritic syndrome
Nephotic Syndrome
-A clinical complex characterized by increased basement membrane permeability due to injury to the capillary walls of the glomeruli
-Characterized by
1. Massive proteinuria >3.5g/day
2. Generalized edema from decreased plasma colloid oncotic pressure
3. Hypoalbunimea secondary to proteinurea
4. Hyperlipidemia and hypercholesterolemia due to increased hepatic lipoprotein synthesis
Nephritic syndrome
-A clinical complex, usually of acute onset, characterized by inflammatory rupture of the glomerular capillaries with resultant bleeding into the urinary space
Characterized by:
1. Oliguria (<400ml)
2. Azotemia (abnormal levels of nitrogen-containing compounds, such as urea, creatinine, various body waste compounds, and other nitrogen-rich compounds in the blood)
3. Hypertension
4. Hematuria with red cell casts
5. Mild proteinuria and edema
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